Antioxidant and antibacterial extracts from rambutan (Nephelium lappaceum) skins: Exploring the Potential of Transforming Agricultural Byproducts into Functional Supplements
Main Article Content
Abstract
Rambutan (Nephelium lappaceum L.) is a tropical fruit characterized by its oval shape and
hairy skin, primarily valued for its juicy pulp. The peels, constituting 45% of the fruit’s weight,
are a source of valuable compounds like geraniin, ellagic acid, and quercetin. These peels
possess antimicrobial properties effective against various bacteria, making them suitable for
food preservation and packaging. Additionally, rambutan extracts hold promise as supplements
in animal feed, enhancing growth and reducing methane production. This research delves into
the antioxidant and antimicrobial attributes of diverse rambutan varieties. The skin (exocarp) of
rambutan fruits from three Costa Rican cultivars -Creole, Rongrein, and Yellow- were collected
and processed. Total polyphenolic content (TPC), proanthocyanidins, antioxidant activity,
geraniin content, and antimicrobial activity were determined for the three varieties. Also,
proanthocyanidin-enriched fractions from rambutan extracts were generated and analyzed.
The results revealed TPC and antioxidant activity variations among different rambutan varieties
and harvest years. All rambutan extracts displayed antimicrobial activity. In conclusion, the
research underscores the rich antioxidant content in rambutan peels, irrespective of the variety,
and underscores their potential for use in both human and animal nutrition due to their chemical
composition.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Los autores conservan los derechos de autor y ceden a la revista el derecho de la primera publicación y pueda editarlo, reproducirlo, distribuirlo, exhibirlo y comunicarlo en el país y en el extranjero mediante medios impresos y electrónicos. Asimismo, asumen el compromiso sobre cualquier litigio o reclamación relacionada con derechos de propiedad intelectual, exonerando de responsabilidad a la Editorial Tecnológica de Costa Rica. Además, se establece que los autores pueden realizar otros acuerdos contractuales independientes y adicionales para la distribución no exclusiva de la versión del artículo publicado en esta revista (p. ej., incluirlo en un repositorio institucional o publicarlo en un libro) siempre que indiquen claramente que el trabajo se publicó por primera vez en esta revista.
References
C. Hernández-Hernández et al., “Rambutan (Nephelium lappaceum L.): Nutritional and functional properties,”
Trends in food science technology, vol. 85, pp. 201-210, 2019.
Z. Tingting, Z. Xiuli, W. Kun, S. Liping, and Z. Yongliang, “A review: extraction, phytochemicals, and biological
activities of rambutan (Nephelium lappaceum L) peel extract,” Heliyon, 2022.
N. N. M. Phuong, T. T. Le, J. Van Camp, and K. Raes, “Evaluation of antimicrobial activity of rambutan
(Nephelium lappaceum L.) peel extracts,” International journal of food microbiology, vol. 321, p. 108539, 2020.
A. Perera, S. H. Ton, and U. D. Palanisamy, “Perspectives on geraniin, a multifunctional natural bioactive compound,” Trends in Food Science Technology, vol. 44, no. 2, pp. 243-257, 2015.
H. S. Cheng, S. H. Ton, and K. Abdul Kadir, “Ellagitannin geraniin: a review of the natural sources, biosynthesis,
pharmacokinetics and biological effects,” Phytochemistry reviews, vol. 16, pp. 159-193, 2017.
K. Mahmood, H. Kamilah, A. K. Alias, and F. Ariffin, “Nutritional and therapeutic potentials of rambutan fruit
(Nephelium lappaceum L.) and the by-products: a review,” Journal of Food Measurement Characterization,
vol. 12, pp. 1556-1571, 2018.
H. Deng et al., “Comparative nutritional and metabolic analysis reveals the taste variations during yellow rambutan fruit maturation,” Food Chemistry: X, vol. 17, p. 100580, 2023.
T. Manso, M. Lores, and T. de Miguel, “Antimicrobial activity of polyphenols and natural polyphenolic extracts
on clinical isolates,” Antibiotics, vol. 11, no. 1, p. 46, 2021.
D. Yun, Y. Qin, J. Zhang, M. Zhang, C. Qian, and J. Liu, “Development of chitosan films incorporated with rambutan (Nephelium lappaceum L.) peel extract and their application in pork preservation,” International Journal
of Biological Macromolecules, vol. 189, pp. 900-909, 2021.
U. Sukatta et al., “Rambutan (Nephelium lappaceum) peel extract: Antimicrobial and antioxidant activities
and its application as a bioactive compound in whey protein isolate film,” Songklanakarin Journal of Science
Technology, vol. 43, no. 1, 2021.
T. Ampapon and M. Wanapat, “Dietary rambutan peel powder as a rumen modifier in beef cattle,” AsianAustralasian Journal of Animal Sciences, vol. 33, no. 5, p. 763, 2020.
C. Le Xuan et al., “Dietary inclusion of rambutan (Nephelium lappaceum L.) seed to Nile tilapia (Oreochromis
niloticus) reared in biofloc system: Impacts on growth, immunity, and immune-antioxidant gene expression,”
Fish Shellfish Immunology, vol. 122, pp. 215-224, 2022.
C. Le Xuan et al., “Effects of dietary rambutan (Nephelium lappaceum L.) peel powder on growth performance,
immune response and immune-related gene expressions of striped catfish (Pangasianodon hypophthalmus)
raised in biofloc system,” Fish Shellfish Immunology, vol. 124, pp. 134-141, 2022.
R. Syedd-León, R. Orozco, V. Álvarez, Y. Carvajal, and G. Rodríguez, “Chemical and antioxidant charaterization of native corn germplasm from two regions of costa rica: A conservation approach,” International journal
of food science, vol. 2020, 2020.
V. Bondet, W. Brand-Williams, and C. Berset, “Kinetics and mechanisms of antioxidant activity using the DPPH.
free radical method,” LWT-Food Science Technology, vol. 30, no. 6, pp. 609-615, 1997.
P. Brescia, “Determination of Antioxidant potential using an Oxygen Radical Absorbance Capacity (ORAC)
Assay with Synergy TM H4,” BioTek Application Note, pp. 4-12, 2012.
A. Tuominen and T. J. P. A. Sundman, “Stability and oxidation products of hydrolysable tannins in basic conditions detected by HPLC/DAD–ESI/QTOF/MS,” vol. 24, no. 5, pp. 424-435, 2013.
B. Vega-López et al., “Phytonutraceutical evaluation of five varieties of tomato (Solanum lycopersicum) during
ripening and processing,” LWT, p. 113592, 2022.
J. Sun, H. Peng, W. Su, J. Yao, X. Long, and J. Wang, “Anthocyanins extracted from rambutan (Nephelium
lappaceum L.) pericarp tissues as potential natural antioxidants,” Journal of Food Biochemistry, vol. 35, no. 5,
pp. 1461-1467, 2011.
S. Das, A. Ray, N. Nasim, S. Nayak, and S. Mohanty, “Effect of different extraction techniques on total phenolic
and flavonoid contents, and antioxidant activity of betelvine and quantification of its phenolic constituents by
validated HPTLC method,” Biotech, vol. 9, no. 1, p. 37, 2019.
E. Cubero‐Román, Y. Carvajal‐Miranda, G. Rodríguez, V. Álvarez‐Valverde, and P. Jiménez‐Bonilla, “Antioxidant
and antimicrobial activity of two Costa Rican cultivars of ber (Ziziphus mauritiana): An underexploited crop in
the American tropic,” Food Science and Nutrition vol. 11, no. 6, pp. 3320-3328, 2023.
N. N. M. Phuong, T. T. Le, M. Q. Dang, J. Van Camp, and K. Raes, “Selection of extraction conditions of phenolic compounds from rambutan (Nephelium lappaceum L.) peel,” Food Bioproducts Processing, vol. 122, pp.
-229, 2020.
N. Thitilertdecha, A. Teerawutgulrag, J. D. Kilburn, and N. Rakariyatham, “Identification of major phenolic
compounds from Nephelium lappaceum L. and their antioxidant activities,” Molecules, vol. 15, no. 3, pp. 1453-
, 2010.
M. K. Roy, M. Koide, T. P. Rao, T. Okubo, Y. Ogasawara, and L. R. Juneja, “ORAC and DPPH assay comparison to assess antioxidant capacity of tea infusions: Relationship between total polyphenol and individual
catechin content,” International journal of food sciences nutrition, vol. 61, no. 2, pp. 109-124, 2010.
E. R. Gullickson, C. G. Krueger, A. Birmingham, M. Maranan, and J. D. Reed, “Development of a cranberry
standard for quantification of insoluble cranberry (Vaccinium macrocarpon Ait.) proanthocyanidins,” Journal of
agricultural food chemistry, vol. 68, no. 10, pp. 2900-2905, 2019.
Q. Qi et al., “Anthocyanins and proanthocyanidins: Chemical structures, food sources, bioactivities, and product development,” Food Reviews International, vol. 39, no. 7, pp. 4581-4609, 2023.